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BRAINAPP

The BrainApp Study is a digital health, multi-centre, observational, non-randomised phase II trial for adult primary brain tumour (BT) patients and healthy volunteers (HVs) in the UK.


The aim of this study is to assess the feasibility, acceptability, and performance of a mobile app, BRIAN, developed by The Brain Tumour Charity, in collecting data on speech, quality of life, physical activity and sleep, for predicting disease progression in adult BT patients.


Subjects will be those aged 16 and above; formally diagnosed with a primary BT (patients only), fluent English speakers, willing and able to undertake study specific measures; and of WHO performance status 0, 1 or 2 (patients only). Patients will be recruited from NHS cancer centres whilst HVs will consist of members of the public, which can be patient caregivers. Participants will be required to enter their speech data on BRIAN along with other information at pre-specified intervals for up to two years.


Researchers will record patient information not captured by BRIAN in electronic case report forms and transfer patient brain imaging to the study management centre at Imperial College London. Data will be analysed using speech processing, repeated measures statistical, traditional machine learning,  and deep learning methods.


BrainApp is now open for recruitment since September 2022.

 

PUBLISHED WORK

BRAINAPP: USING NEAR-PATIENT SENSING THROUGH A MOBILE APP AND MACHINE LEARNING IN BRAIN TUMOUR PATIENTS

October 2021

Nur Aizaan Anwar, Matthew Williams